What is your price range?
How far are you willing to commute?
Is it important to be close to a school, a place of worship, etc.?
What type of lot or yard do you want or need?
Do you need a garage? (How large? Attached or unattached?)
How much maintaining or updating are you willing to do?
How many bedrooms/bathrooms do you need?
What other requirements do you have? (# of levels, size, storage, etc.)